Name

On going research title

Research periode

• Alternative squalene sebagai adjuvant vaksin;

• Alternative squalene as a vaccine adjuvant;

• ekstrak tanaman obat sebagai antikolitis;

• medicinal plant extracts as anticolitis;

• identifikasi alergen lokal Indonesia

• identification of local Indonesian allergens

• Willingness to pay for preventive and promotive programs in Indonesia;
• Telemedicine and its utilization among Indonesian population;
• Availability and accessability of controlled medicines in Indonesia

• Formulasi sediaan farmasi,

• Pharmaceutical preparation formulations,

• penelitian terkait eksipien

• Excipient related research

• Functional drug-gene target disease analysis of flavonoids and alkaloids for overcoming HER2+ breast cancer resistance towards targeted therapy.

• Reverse vaccinology against breast cancer and tropical disease

• Pengembangan bahan alam Indonesia untuk antiinfeksi

• Development of Indonesian natural ingredients for anti-infection

• Discovery of Bioactive Compounds from Sukun (Artocarpus altilis) and Jotang (Acmella oleracea)
• Ethnopharmacological survey of Indonesian Herbal medicines

• Pengembangan Metode Deteksi Komponen Non-Halal Pada Produk Olahan Pangan Melalui Pendekatan Metabolomik Dan Proteomik Dengan LC-HRMS

• Development of a Method for Detecting Non-Halal Components in Processed Food Products Using a Metabolomics and Proteomics Approach Using LC-HRMS

• Pengembangan Senyawa Kurkumin Analog Tertarget NCYM

• Development of NCYM Targeted Analog Curcumin Compounds

• Pengembangan Senyawa Modulator Pyroptosis

• Development of Pyroptosis Modulator Compounds

• Pengembangan Senyawa Flavonoid dari Citrus sp. sebagai Agen Ko-Kemoterapi Kanker, Anti-aging, Anti-aterosklerosis, dan Imunomodulator

• Development of Flavonoid Compounds from Citrus sp. as a Cancer Chemotherapy Agent, Anti-aging, Anti-atherosclerosis, and Immunomodulator

• Optimasi ekstraksi daun binahong dan herba pegagan

• Optimization of extraction of binahong leaves and gotu kola herb

• Health-seeking, medicine-taking behaviors and social supports in people with stigmatized conditions

• Penemuan dan Rancangan Calon Obat Baru Dari Bahan Alam dan Hasil Sintesis untuk:

1. Brain disorder (Alzheimer, learning and memory, social interaction, anxiety, depression)
2. Neurogenesis dan gliogenesis
3. Mekanisme epigenetik
4. Diferensiasi neural stem cellls
5. Diabetes, Hipertensi, Dislipidemia
6. Analgetik, antipiretik, antiinflamasi (akut dan kronis, perifer dan pusat)
7. Antiobesitas (antioksidan dan lipase inhibitor)

• Surveillans penggunaan antimikroba (kualitatif dan kuantitatif)

• Discovery and Design of New Drug Candidates from Natural Ingredients and Synthesis Results for:

1. Brain disorders (Alzheimer’s, learning and memory, social interaction, anxiety,depression)
2. Neurogenesis and gliogenesis
3. Epigenetic mechanisms
4. Differentiation of neural stem cells
5. Diabetes, Hypertension, Dyslipidemia
6. Analgesic, antipyretic, anti-inflammatory (acute and chronic, peripheral and central)
7. Antiobesity (antioxidant and lipase inhibitor)

• Surveillance of antimicrobial use (qualitative and quantitative)

• Identifikasi Protein Toksik di dalam jamur merang, karakterisasi, uji toksisitas dan uji bioaktivitasnya

• Identification of Toxic Proteins in straw mushrooms, characterization, toxicity tests and bioactivity tests

• Pengembangan analog kurkumin sebagai antihipertensi, studi in vitro dan in silico

• Development of curcumin analogs as antihypertensives, in vitro and in silico studies

• Pengembangan metode analisis autentifikasi halal dengan metode PCR

• Development of halal authentication analysis methods using the PCR method

• Karakterisasi bioaktif dalam kalus yang ditumbuhkan dari tanaman sebagai antiaging

• Characterization of bioactives in callus grown from plants as antiaging

• Pengembangan produk nutrasetikal dan pangan fungsional untuk penyakit degeneratif dan penvegahan stunting

• Development of nutraceutical products and functional foods for degenerative diseases and preventing stunting

• Pengaruh polimorfisme gen UGT1A9 dan IMDH2 terhadap outcome terapi obat mikofenolat pada pasien yang menerima transplantasi ginjal dan penyakit autoimun

• The influence of UGT1A9 and IMDH2 gene polymorphisms on the outcome of mycophenolate drug therapy in patients receiving kidney transplants and autoimmune diseases

• Pengembangan poliherbal untuk terapi ulkus diabetes

• Development of polyherbals for diabetic ulcer therapy

• Pengembagan ekstrak kayu secang sebagai cognitive enhancer

• Development of secang wood extract as a cognitive enhancer

• Studi farmakogenomik pada beberapa penyakit dan obatnya

• Pharmacogenomic studies on several diseases and their drugs

tps://acadstaff.ugm.ac.id/Zullies

• The Exploration of Herbal Medicine : From the active compound to investigation of molecular action. Project : “Combination of Sambiloto Fraction (Andrographis paniculata) rich in Andrographolide and Ginger Fraction (Zingiber officinale) rich in 6-Shogaol as a Potent Anti-diabetic Neuropathy: Pharmacological Study, Mechanism of Action Investigation and Product Prototype Development

• Exploring The Potential of Indonesian natural products as anti-microbial quorum sensing

• ANALISIS FARMAKOEKONOMI BERBASIS MODELING TERHADAP VAKSINASI HUMAN PAPILLOMAVIRUS UNTUK MENCEGAH PENYAKIT KANKER NON-SERVIKS YANG DISEBABKAN OLEH VIRUS HUMAN PAPILLOMAVIRUS DI INDONESIA

• MODELING-BASED PHARMACOECONOMIC ANALYSIS OF HUMAN PAPILLOMAVIRUS VACCINATION TO PREVENT NON-CERVICAL CANCER DISEASES CAUSED BY HUMAN PAPILLOMAVIRUS VIRUS IN INDONESIA

• Pemurnian Parasetamol melalui Rekristalisasi Dengan Penambahan Asam Hidroksikarboksilat sebagai Agen Ko-Kristalisasi

• Purification of Paracetamol Through Recrystallization with Addition of Hydroxycarboxylic Acid As the Co-Crystallization Agent

• Aplikasi Modeling Berbasis Populasi dalam Therapeutic Drug Monitoring Meropenem

• Application of Population-Based Modeling in Therapeutic Drug Monitoring Meropenem

• Penemuan dan pengembangan obat dari bahan alam, sintetik dan produk biologis sebagai antikanker/Drug discovery and development from natural, synthetic and biological products as anti-inflammatory, anti-cancer, and anti-ageing agents

• Drug discovery and development from natural, synthetic and biological products as anti-cancer/Drug discovery and development from natural, synthetic and biological products as anti-inflammatory, anti-cancer, and anti-aging agents

• Pengembangan eksosom dan sekretom dari stem cell untuk penyakit sistem imun, kanker dan aging/Development of exosomes and secretomes derived from stem cells for immune system diseases, cancer and ageing.

• Development of exosomes and secretomes derived from stem cells for immune system diseases, cancer and aging.

• Pengembangan senyawa dari bahan alam untuk imunomodulator, penyakit sistem imun dan kesembuhan luka/Development of compounds from natural ingredients for immunomodulation, immune system diseases and wound healing.

• Development of compounds from natural ingredients for immunomodulation, immune system diseases and wound healing

apt. Puguh Indrasetiawan, M.Sc., Ph.D.

Dr. apt. Fita Rahmawati, Sp.FRS.